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4In 2007, Barrangou et al. demonstrated for the first time the function of CRISPR/Cas9 as a defensive mechanism of bacteria against bacteriophage attacks by a technique called “plaquing” which builds upon the technique of “plating” bacteria on agar. Plaques of viruses on agar are areas without growth of bacteria due to viral attacks.
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The Streams Standard was developed between 2014 and 2016 with an ambitious goal to provide "APIs for creating, composing, and consuming streams of data that map efficiently to low-level I/O primitives." Before Web streams, the web platform had no standard way to work with streaming data.，这一点在im钱包官方下载中也有详细论述
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